The hepatology research group (HRG) is an integral part of the Institute of Health and Care Research: infection, immunity and inflammation.
We utilise state of the art laboratory facilities based in the Derriford Research Facility, and the world class clinical research strengths of the Faculty of Health and University Hospitals Plymouth NHS Trust.
We work in unison with the South West Liver Unit, at University Hospitals Plymouth NHS Trust, providing a full range and secondary, tertiary and community Hepatology services to the South West region, including assessment for liver transplantation, TIPS and liver cancer therapy.
The research team run several commercially sponsored clinical trials in hepatitis C therapy, non-alcoholic steatohepatitis (NASH), primary biliary cholangiopathy (PBC), alcoholic liver disease and liver failure amongst others, through the clinical research facilities of The Lind Research Centre at Derriford Hospital.
Hepatology Research Group Annual Reports
Hepatology research group themes
Publications
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2023 'Assessment of immune function and prediction of survival and infection in patients with severe alcoholic hepatitis: An exploratory study' JGH Open , DOI Open access
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2023 'Satellite liver transplant centres significantly improve transplant assessment outcomes for patients with chronic liver disease but not hepatocellular carcinoma: a retrospective cohort study' Frontline Gastroenterology 14, (4) 334-342 , DOI
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2022 'Deaths from alcohol-related liver disease in the UK: an escalating tragedy' The Lancet 401, (10375) 418-420 , DOI
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2022 'Infection with the hepatitis C virus causes viral genotype-specific differences in cholesterol metabolism and hepatic steatosis' Scientific Reports 12, (1) , DOI Open access
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2022 'A phase II, randomized, open-label, 52-week study of seladelpar in patients with primary biliary cholangitis' Journal of Hepatology , DOI Open access
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2022 'Patients with moderate to severe COVID-19 have an impaired cytokine response with an exhausted and senescent immune phenotype' Immunobiology 227, (2) , DOI Open access
Hepatology research group team
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Professor Matthew Cramp
Chair in Hepatology
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Dr David Sheridan
Associate Professor & Honorary Consultant in Hepatology
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Dr Ashwin Dhanda
Honorary Associate Professor in Hepatology
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Dr Daniel Felmlee
Lecturer in Hepatology
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Paula Boeira
Technician
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Miss Justyna Lopatecka
Technical Specialist
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Miss Hannah Windmill
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Ms Namrata Pandey
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Dr Prebashan Moodley
NIHR Academic Clinical Fellow
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Dr Kristopher Bennett