Parkinson’s disease (PD) and Dementia with Lewy bodies (DLB) are neurodegenerative diseases that both see nerve cells in the brain die or malfunction. When this happens, patients can experience issues such as tremors, slowness of movement, muscle stiffness, nerve pain, memory loss, and reduced motivation. Currently there is no treatment available that can cure PD or DLB.
Researchers at the University of Plymouth, led by Professor Edgar Kramer, are seeking to understand the causes and mechanisms that lead to the nerve cell deaths, with a vision towards improving current therapies for patients.
Currently there are two projects underway at the University funded by the charity BRACE, a key funder in dementia research since 1987, that aim to uncover the answers to key questions on the functions of proteins in the brain and how they work. The projects focus on applying new knowledge to inform novel methods of treating PD and DLB, and to improve the current care practices to grant patients a better quality of life.