Dr Chiara Boschetti
Profiles

Dr Chiara Boschetti

Lecturer in Biological Sciences

School of Biological and Marine Sciences (Faculty of Science and Engineering)

Biography

Biography

Lecturer in Biological Sciences
Co-organiser of the School of Biological and Marine Sciences External Seminar Series
Organiser of the Molecular Breakfast and Bioinformatics Club internal series
Previous roles
Senior Research Associate, Department of Chemical Engineering and Biotechnology, University of Cambridge, UK & Head of Biology, Cambridge Infinitus Research Centre, University of Cambridge, UK
Post-Doctoral Research Associate, Department of Chemical Engineering and Biotechnology, University of Cambridge, UK
Research visitor, Department of Life Sciences, Imperial College London, UK
PhD in Animal Biology, Department of Biology, Università degli Studi di Milano, Italy
Professional membership
Fellow of Higher Education Academy
Roles on external bodies
Reviewer for various Journals including Science, PLoS ONE, Biological Journal of the Linnean Society, Comparative Biochemistry and Physiology, Evolution, Genome Biologyand Evolution, Hydrobiologia, Gene, Cell Stress & Chaperones, Scientific Reports.
Teaching

Teaching

Teaching interests

Main teaching interests: zoology, comparative genomics, evolution, physiology of stress resistance, cell and molecular biology, microscopy.
Research

Research

Research interests

Comparative genomics of stress-resistant micro-metazoans (rotifers, tardigrades and nematodes).
Publications

Publications

Journals
Cesari M. C Boschetti & TC Boothby (2023). Editorial: Physiology of invertebrate sensing in extreme conditions and hostile environment. Front Physiol 14: 1334716.

M Lu, A Mishra, C Boschetti, J Lin, Y Liu, H Huang, CF Kaminski, Z Huang, A Tunnacliffe & GS Kaminski Schierle (2021). Sea cucumber-derived peptides alleviate oxidative stress in neuroblastoma cells and improve survival in C. elegans exposed to neurotoxic paraquat. Oxid Med Cell Long 2021: 8842926.

Rebecchi L, C Boschetti & DR Nelson (2020). Extreme-tolerance mechanisms in meiofaunal organisms: a case study with tardigrades, rotifers and nematodes. Hydrobiologia 847: 2779-2799.

Nowell RW, P Almeida, CG Wilson, TP Smith, D Fontaneto, A Crisp, G Micklem, A Tunnacliffe, C Boschetti & TG Barraclough (2018). Comparative genomics of bdelloid rotifers: insights from desiccating and non desiccating species. PLoS Biol 16(4): e2004830.

Barbosa EGG, A Crisp, S Broadbent, M Carrillo, C Boschetti & A Tunnacliffe (2016). A functional difference between native and horizontally acquired genes in bdelloid rotifers. Gene 590: 186-191.

Eyres I, C Boschetti, A Crisp, D Fontaneto, A Tunnacliffe & TG Barraclough (2015). Horizontal gene transfer in bdelloid rotifers is ancient, ongoing and more frequent in species from desiccating habitats. BMC Biol 13: 90.

Lu M, C Boschetti & A Tunnacliffe (2015). Long term aggresome accumulation leads to DNA damage, p53-dependent cell cycle arrest, and steric interference in mitosis. J Biol Chem 290: 27986-28000.

Crisp A, C Boschetti, M Perry, A Tunnacliffe & G Micklem (2015). Expression of multiple horizontally acquired genes is a hallmark of both vertebrate and invertebrate genomes. Genome Biol 16: 50.

Lu M, N Williamson, C Boschetti, T Ellis, T Yoshimi & A Tunnacliffe (2015). Expression-level dependent perturbation of cell proteostasis and nuclear morphology by aggregation-prone polyglutamine proteins. Biotech Bioeng 112: 1883-1892.

Szydlowski L, C Boschetti, A Crisp, EGG Barbosa, G Micklem & A Tunnacliffe (2015). Multiple horizontally acquired genes encode cellulose-digesting enzymes in the bdelloid rotifer Adineta ricciae. Gene 566: 125-137.

Boschetti C, A Crisp, G Micklem, MJ Wise & A Tunnacliffe (2013). Anhydrobiosis: the curious case of the bdelloid rotifer. Cryobiol Cryotechnol 59: 29-34.

Boschetti C, A Carr, A Crisp, I Eyres, Y Wang-Koh, E Lubzens, TG Barraclough, G Micklem & A Tunnacliffe (2012). Biochemical diversification through foreign gene expression in bdelloid rotifers. PLoS Genet 8(11): e1003035.

Eyres I, E Frangedakis, D Fontaneto, EA Herniou, C Boschetti, A Carr, G Micklem, A Tunnacliffe & TG Barraclough (2012). Multiple functionally divergent and conserved copies of alpha tubulin in bdelloid rotifers. BMC Evol Biol 12: 148.

Tripathi R, C Boschetti, B McGee & A Tunnacliffe (2012). Trafficking of bdelloid rotifer late embryogenesis abundant proteins. J Exp Biol 215: 2786-2794.

Boschetti C, F Leasi & C Ricci (2011). Developmental stages in diapausing eggs: an investigation across monogonont rotifer species. Hydrobiol 662: 149-155.

Boschetti C, N Pouchkina-Stantcheva, P Hoffmann & A Tunnacliffe (2011). Foreign genes and novel hydrophilic protein genes participate in the desiccation response of the bdelloid rotifer Adineta ricciae. J Exp Biol 214: 59-68.

Wang X, C Boschetti, MJ Ruedas-Rama, A Tunnacliffe & EAH Hall (2010). Ratiometric pH-dot ANSors. Analyst 135: 1585-1591.

Fontaneto D, C Boschetti & C Ricci (2008). Cryptic diversification in ancient asexuals: evidence from the bdelloid rotifer Philodina flaviceps. J Evol Biol 21: 580-587.

Pouchkina-Stantcheva NN, BM McGee, C Boschetti, D Tolleter, S Chakrabortee, AV Popova, F Meersman, D Macherel, DK Hincha & A Tunnacliffe (2007). Functional divergence of former alleles in an ancient asexual invertebrate. Science 318: 268-271.

Fontaneto D, EA Herniou, C Boschetti, M Caprioli, G Melone, C Ricci & TG Barraclough (2007). Independently evolving species in asexual bdelloid rotifers. PLoS Biol 5(4): e87.

Chakrabortee S, C Boschetti, LJ Walton, S Sarkar, DC Rubinsztein & A Tunnacliffe (2007). Hydrophilic protein associated with desiccation tolerance exhibits broad protein stabilization function. Proc Natl Acad Sci U S A 104: 18073-18078.

Ricci C, M Caprioli, C Boschetti & N Santo (2005). Macrotrachela quadricorniferafeatured in a space experiment. Hydrobiol 534: 239-244.

Boschetti C, C Ricci, C Sotgia & U Fascio (2005). The development of a bdelloid egg: a contribution after 100 years. Hydrobiol 546: 323-331.

Ricci C & C Boschetti (2003). Bdelloid rotifers as model system to study developmental biology in space. Adv Space Biol Med 9: 25-39.


Chapters
Personal

Personal

Reports & invited lectures

Selected invited talks
Invited seminar, Stokes Society, Pembroke College, University of Cambridge (2019)
Invited plenary talk, International Congress on Invertebrate Pathology and Microbial Control and the 49th Annual Meeting of the Society for Invertebrate Pathology, Tours, France (2016)
Invited plenary talk, XIII International Symposium on Tardigrada, Modena, Italy (2015)
Selected seminar, Evolutionary Genetics & Genomics Symposium, University of Cambridge (2015)
Invited seminar, Crossing the Barriers lecture series - Evolution, University of Cambridge (2015)
Invited seminar, Department of Zoology, University of Cambridge (2015).