Professor Raymond Playford
Profiles

Professor Raymond Playford

Professor of Medicine

Peninsula Medical School (Faculty of Health: Medicine, Dentistry and Human Sciences)

Role

Deputy Vice Chancellor

Professional membership

Fellow Royal College Physicians
Fellow Royal College Pathologists
Fellow Academy of Medical Science
Member British Society Gastroenterology
Member American Gastroenterology Association

Research interests

Mechanisms of repair
Nutriceuticals
Nutrition
Inflammatory Bowel Disease
Barrett's Oesophagus

Key publications are highlighted

Journals
Articles
Davison G, Jones AW, Marchbank T & Playford RJ 2019 'Oral bovine colostrum supplementation does not increase circulating insulin-like growth factor-1 concentration in healthy adults: results from short- and long-term administration studies' European Journal of Nutrition , DOI PEARL
Marchbank T & Playford R 2017 'Specific protein supplementation using soya, casein or whey differentially affects regional gut growth and luminal growth factor bioactivity in rats; implications for the treatment of gut injury and stimulating repair' Food and Function , DOI PEARL
Marchbank T & Playford RJ 2017 'Trefoil factor family peptides enhance cell migration by increasing cellular osmotic permeability and aquaporin 3 levels' FASEB Journal , DOI PEARL
March DS, Marchbank T, Playford RJ, Jones AW, Thatcher R & Davison G 2017 'Intestinal fatty acid-binding protein and gut permeability responses to exercise' European Journal of Applied Physiology 117, (5) 931-941 , DOI PEARL
Davison G, Marchbank T, March DS, Thatcher R & Playford RJ 2016 'Zinc carnosine works with bovine colostrum in truncating heavy exercise-induced increase in gut permeability in healthy volunteers' American Journal of Clinical Nutrition Author Site , DOI PEARL
Marchbank T, Mahmood A & Playford RJ 2013 'Pancreatic secretory trypsin inhibitor causes autocrine-mediated migration and invasion in bladder cancer and phosphorylates the EGF receptor, Akt2 and Akt3, and ERK1 and ERK2' Am J Physiol Renal Physiol 305, (3) F382-F389 Author Site , DOI
Playford RJ, Pither C, Gao R & Middleton SJ 2013 'Use of the Alpha-Glucosidase Inhibitor Acarbose in Patients with ‘Middleton Syndrome’: Normal Gastric Anatomy But with Accelerated Gastric Emptying Causing Postprandial Reactive Hypoglycemia and Diarrhea' Canadian Journal of Gastroenterology 27, (7) 403-404 , DOI
Raymond M, Marchbank T, Moyer MP, Playford RJ, Sanderson IR & Kruidenier L 2012 'IL-1β stimulation of CCD-18co myofibroblasts enhances repair of epithelial monolayers through Wnt-5a' Am J Physiol Gastrointest Liver Physiol , DOI
Marchbank T, Mahmood A, Harten S, Maxwell PH & Playford RJ 2011 'Dimethyloxalyglycine stimulates the early stages of gastrointestinal repair processes through VEGF-dependent mechanisms' Lab Invest 91, (12) 1684-1694 Author Site , DOI
Marchbank T, Ojobo E, Playford CJ & Playford RJ 2011 'Reparative properties of the traditional Chinese medicine Cordyceps sinensis (Chinese caterpillar mushroom) using HT29 cell culture and rat gastric damage models of injury' Br J Nutr 105, (9) 1303-1310 Author Site , DOI
Marchbank T, Davison G, Oakes JR, Ghatei MA, Patterson M, Moyer MP & Playford RJ 2011 'The nutriceutical bovine colostrum truncates the increase in gut permeability caused by heavy exercise in athletes' Am J Physiol Gastrointest Liver Physiol 300, (3) G477-G484 Author Site , DOI
Marchbank T, Elia G & Playford RJ 2009 'Intestinal protective effect of a commercial fish protein hydrolysate preparation' Regul Pept 155, (1-3) 105-109 Author Site , DOI
Jhavar S, Brewer D, Edwards S, Kote-Jarai Z, Attard G, Clark J, Flohr P, Christmas T, Thompson A 2009 'Integration of ERG gene mapping and gene-expression profiling identifies distinct categories of human prostate cancer' BJU Int 103, (9) 1256-1269 , DOI
Marchbank T, Elia G & Playford RJ 2009 'INTESTINAL PROTECTIVE EFFECT OF A COMMERCIAL FISH PROTEIN HYDROLYSATE PREPARATION' GUT 58, A46-A47 Author Site
Marchbank T, Weaver G, Nilsen-Hamilton M & Playford RJ 2009 'Pancreatic secretory trypsin inhibitor is a major motogenic and protective factor in human breast milk' Am J Physiol Gastrointest Liver Physiol 296, (4) G697-G703 Author Site , DOI
Huang N, Bethell D, Card C, Cornish J, Marchbank T, Wyatt D, Mabery K & Playford R 2008 'Bioactive recombinant human lactoferrin, derived from rice, stimulates mammalian cell growth' In Vitro Cell Dev Biol Anim 44, (10) 464-471 Author Site , DOI
Playford RJ & Ghosh S 2008 'What is the role of growth factors in IBD?' Inflamm Bowel Dis 14 Suppl 2, S119-S120 Author Site , DOI
Marchbank T, Limdi JK, Mahmood A, Elia G & Playford RJ 2008 'Clinical trial: protective effect of a commercial fish protein hydrolysate against indomethacin (NSAID)-induced small intestinal injury' Aliment Pharmacol Ther 28, (6) 799-804 Author Site , DOI
Marion-Letellier R, Butler M, Déchelotte P, Playford RJ & Ghosh S 2008 'Comparison of cytokine modulation by natural peroxisome proliferator-activated receptor gamma ligands with synthetic ligands in intestinal-like Caco-2 cells and human dendritic cells--potential for dietary modulation of peroxisome proliferator-activated receptor gamma in intestinal inflammation' Am J Clin Nutr 87, (4) 939-948
Hunt KA, Zhernakova A, Turner G, Heap GAR, Franke L, Bruinenberg M, Romanos J, Dinesen LC, Ryan AW 2008 'Newly identified genetic risk variants for celiac disease related to the immune response' Nat Genet 40, (4) 395-402 Author Site , DOI
Butler M, Chaudhary R, van Heel DA, Playford RJ & Ghosh S 2007 'NOD2 activity modulates the phenotype of LPS-stimulated dendritic cells to promote the development of T-helper type 2-like lymphocytes - Possible implications for NOD2-associated Crohn's disease' J Crohns Colitis 1, (2) 106-115 Author Site , DOI
Marchbank T, Mahmood A, Fitzgerald AJ, Domin J, Butler M, Goodlad RA, Elia G, Cox HM, van Heel DA 2007 'Human pancreatic secretory trypsin inhibitor stabilizes intestinal mucosa against noxious agents' Am J Pathol 171, (5) 1462-1473 Author Site , DOI
Butler M, Boyle JJ, Powell JJ, Playford RJ & Ghosh S 2007 'Dietary microparticles implicated in Crohn's disease can impair macrophage phagocytic activity and act as adjuvants in the presence of bacterial stimuli' Inflamm Res 56, (9) 353-361 , DOI
van Heel DA, Franke L, Hunt KA, Gwilliam R, Zhernakova A, Inouye M, Wapenaar MC, Barnardo MCNM, Bethel G 2007 'A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21' Nat Genet 39, (7) 827-829 Author Site , DOI
Mahmood A, FitzGerald AJ, Marchbank T, Ntatsaki E, Murray D, Ghosh S & Playford RJ 2007 'Zinc carnosine, a health food supplement that stabilises small bowel integrity and stimulates gut repair processes' Gut 56, (2) 168-175 , DOI
van Bodegraven AA, Curley CR, Hunt KA, Monsuur AJ, Linskens RK, Onnie CM, Crusius JB, Annese V, Latiano A 2006 'Genetic variation in myosin IXB is associated with ulcerative colitis' Gastroenterology 131, (6) 1768-1774 , DOI
van Heel DA & Playford RJ 2006 'Response' European Journal of Immunology 36, (10) 2818-2819 , DOI
Playford RJ, Belo A, Poulsom R, Fitzgerald AJ, Harris K, Pawluczyk I, Ryon J, Darby T, Nilsen-Hamilton M 2006 'Effects of mouse and human lipocalin homologues 24p3/lcn2 and neutrophil gelatinase-associated lipocalin on gastrointestinal mucosal integrity and repair' Gastroenterology 131, (3) 809-817 , DOI
Ghosh S, Chaudhary R, Carpani M & Playford R 2006 'Interfering with interferons in inflammatory bowel disease' Gut 55, (8) 1071-1073 Author Site , DOI
Gordon MY, Levicar N, Pai M, Bachellier P, Dimarakis I, Al-Allaf F, M'Hamdi H, Thalji T, Welsh JP 2006 'Characterization and clinical application of human CD34+ stem/progenitor cell populations mobilized into the blood by granulocyte colony-stimulating factor' Stem Cells 24, (7) 1822-1830 Author Site , DOI
van Heel DA, Hunt KA, King K, Ghosh S, Gabe SM, Mathew CG, Forbes A & Playford RJ 2006 'Detection of muramyl dipeptide-sensing pathway defects in patients with Crohn's disease' Inflamm Bowel Dis 12, (7) 598-605 , DOI
Hunt KA, Monsuur AJ, McArdle WL, Kumar PJ, Travis SP, Walters JR, Jewell DP, Strachan DP, Playford RJ 2006 'Lack of association of MYO9B genetic variants with coeliac disease in a British cohort' Gut 55, (7) 969-972 , DOI
van Heel DA, Hunt KA, Ghosh S, Hervé M & Playford RJ 2006 'Normal responses to specific NOD1-activating peptidoglycan agonists in the presence of the NOD2 frameshift and other mutations in Crohn's disease' Eur J Immunol 36, (6) 1629-1635 Author Site , DOI
Cibrián D, Ajamieh H, Berlanga J, León OS, Alba JS, Kim MJ-T, Marchbank T, Boyle JJ, Freyre F 2006 'Use of growth-hormone-releasing peptide-6 (GHRP-6) for the prevention of multiple organ failure' Clin Sci (Lond) 110, (5) 563-573 Author Site , DOI
Butler M, Ng C-Y, van Heel DA, Lombardi G, Lechler R, Playford RJ & Ghosh S 2006 'Modulation of dendritic cell phenotype and function in an in vitro model of the intestinal epithelium' Eur J Immunol 36, (4) 864-874 Author Site , DOI
Playford RJ 2006 'New British Society of Gastroenterology (BSG) guidelines for the diagnosis and management of Barrett's oesophagus' Gut 55, (4) Author Site , DOI
Direkze NC, Jeffery R, Hodivala-Dilke K, Hunt T, Playford RJ, Elia G, Poulsom R, Wright NA & Alison MR 2006 'Bone marrow-derived stromal cells express lineage-related messenger RNA species' Cancer Res 66, (3) 1265-1269 Author Site , DOI
Belo A, Marchbank T, Fitzgerald A, Ghosh S & Playford RJ 2006 'Gastroprotective effects of oral nucleotide administration' Gut 55, (2) 165-171 , DOI
Ghosh S, Chaudhary R, Carpani M & Playford RJ 2006 'Is thiopurine therapy in ulcerative colitis as effective as in Crohn's disease?' Gut 55, (1) 6-8 Author Site , DOI
van Heel DA, Ghosh S, Hunt KA, Mathew CG, Forbes A, Jewell DP & Playford RJ 2005 'Synergy between TLR9 and NOD2 innate immune responses is lost in genetic Crohn's disease' Gut 54, (11) 1553-1557 , DOI
van Heel DA, Dart J, Nichols S, Jewell DP & Playford RJ 2005 'Novel presentation of coeliac disease after following the Atkins' low carbohydrate diet' Gut 54, (9) Author Site , DOI
van Heel DA, Ghosh S, Butler M, Hunt K, Foxwell BMJ, Mengin-Lecreulx D & Playford RJ 2005 'Synergistic enhancement of Toll-like receptor responses by NOD1 activation' Eur J Immunol 35, (8) 2471-2476 Author Site , DOI
Kitchen PA, Goodlad RA, FitzGerald AJ, Mandir N, Ghatei MA, Bloom SR, Berlanga-Acosta J, Playford RJ, Forbes A, et. al 2005 'Intestinal growth in parenterally-fed rats induced by the combined effects of glucagon-like peptide 2 and epidermal growth factor' JPEN J Parenter Enteral Nutr 29, (4) 248-254
Fitzgerald AJ, Rai PS, Marchbank T, Taylor GW, Ghosh S, Ritz BW & Playford RJ 2005 'Reparative properties of a commercial fish protein hydrolysate preparation' Gut 54, (6) 775-781 Author Site , DOI
Mahmood A, Melley L, Fitzgerald AJ, Ghosh S & Playford RJ 2005 'Trial of trefoil factor 3 enemas, in combination with oral 5-aminosalicylic acid, for the treatment of mild-to-moderate left-sided ulcerative colitis' Aliment Pharmacol Ther 21, (11) 1357-1364 , DOI
van Heel DA, Ghosh S, Butler M, Hunt KA, Lundberg AMC, Ahmad T, McGovern DPB, Onnie C, Negoro K 2005 'Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease' Lancet 365, (9473) 1794-1796 Author Site , DOI
Albrecht C, Soumian S, Playford R, Higgins CF, Vyse T & Elliott J 2005 'Accelerated exposure of phosphatidylserine on lymphocyte populations from patients with systemic lupus erythematosus or rheumatoid arthritis' Thromb Haemost 93, (5) 989-992 Author Site
Hunt KA, McGovern DPB, Kumar PJ, Ghosh S, Travis SPL, Walters JRF, Jewell DP, Playford RJ & van Heel DA 2005 'A common CTLA4 haplotype associated with coeliac disease' Eur J Hum Genet 13, (4) 440-444 Author Site , DOI
Playford RJ & Ghosh S 2005 'Cytokines and growth factor modulators in intestinal inflammation and repair' J Pathol 205, (4) 417-425 Author Site , DOI
Playford RJ 2005 'The value of surveillance and other unresolved issues in the management of Barrett's esophagus' Nat Clin Pract Gastroenterol Hepatol 2, (2) 60-61 Author Site , DOI
Playford RJ, Ghosh S & Mahmood A 2004 'Growth factors and trefoil peptides in gastrointestinal health and disease' Curr Opin Pharmacol 4, (6) 567-571 Author Site , DOI
Playford RJ, Wassan H & Ghosh S 2004 'Effects of growth factors and receptor blockade on gastrointestinal cancer' Gut 53, (8) 1059-1063 Author Site , DOI
Pu M, May FEB, Playford RJ, Ruchaud-Sparagano M-H & Westley BR 2004 'Development of a two-site ELISA assay for the dimeric form of human TFF1' Peptides 25, (5) 731-736 Author Site , DOI
Ghosh S, van Heel D & Playford RJ 2004 'Probiotics in inflammatory bowel disease: is it all gut flora modulation?' Gut 53, (5) 620-622 Author Site , DOI
FitzGerald AJ, Pu M, Marchbank T, Westley BR, May FEB, Boyle J, Yadollahi-Farsani M, Ghosh S & Playford RJ 2004 'Synergistic effects of systemic trefoil factor family 1 (TFF1) peptide and epidermal growth factor in a rat model of colitis' Peptides 25, (5) 793-801 Author Site , DOI
Playford RJ 2004 'The challenges of Barrett's -- suppression, symptoms or surveillance' Best Pract Res Clin Gastroenterol 18 Suppl, 47-53 Author Site , DOI
Bashir O, Fitzgerald AJ, Berlanga-Acosta J, Playford RJ & Goodlad RA 2003 'Effect of epidermal growth factor administration on intestinal cell proliferation, crypt fission and polyp formation in multiple intestinal neoplasia (Min) mice' Clin Sci (Lond) 105, (3) 323-330 Author Site , DOI
Sinha A, Nightingale J, West KP, Berlanga-Acosta J & Playford RJ 2003 'Epidermal growth factor enemas with oral mesalamine for mild-to-moderate left-sided ulcerative colitis or proctitis' N Engl J Med 349, (4) 350-357 , DOI
Thomas PD, Forbes A, Green J, Howdle P, Long R, Playford R, Sheridan M, Stevens R, Valori R 2003 'Guidelines for the investigation of chronic diarrhoea, 2nd edition' Gut 52 Suppl 5, v1-15 Author Site , DOI
Ghosh S & Playford RJ 2003 'Bioactive natural compounds for the treatment of gastrointestinal disorders' Clin Sci (Lond) 104, (6) 547-556 Author Site , DOI
Belo AC & Playford RJ 2003 'Surveillance for Barrett's oesophagus: is there light the end of the metaplastic tunnel?' Surgeon 1, (3) 152-156 Author Site
Mandal A, Playford RJ & Wicks AC 2003 'Current practice in surveillance strategy for patients with Barrett's oesophagus in the UK' Aliment Pharmacol Ther 17, (10) 1319-1324
Marchbank T, Boulton R, Hansen H & Playford RJ 2003 'Human transforming growth factor a (TGF-alpha) is digested to a smaller (1-43), less biologically active, form in acidic gastric juice (vol 51, pg 787, 2002)' GUT 52, (2) 315-315 Author Site
Moss SF, Armstrong D, Arnold R, Ferenci P, Fock KM, Holtmann G, McCarthy DM, Moraes-Filho JP, Mutschler E 2003 'GERD 2003 -- a consensus on the way ahead' Digestion 67, (3) 111-117 Author Site , DOI
Marchbank T, Boulton R, Hansen H & Playford RJ 2002 'Human transforming growth factor alpha (TGF-alpha) is digested to a smaller (1-43), less biologically active, form in acidic gastric juice' Gut 51, (6) 787-792
Khan Z, Macdonald C, Wicks AC, Holt MP, Floyd D, Ghosh S, Wright NA & Playford RJ 2002 'Use of the 'nutriceutical', bovine colostrum, for the treatment of distal colitis: results from an initial study' Aliment Pharmacol Ther 16, (11) 1917-1922
Playford RJ 2002 'Antagonist: endoscopic surveillance of patients with Barrett's oesophagus' Gut 51, (3) 314-315 Author Site , DOI
Playford RJ 2002 'Endoscopic surveillance of patients with Barrett's oesophagus' GUT 51, (3) 314-315 Author Site , DOI
Arebi N, Healey ZV, Bliss PW, Ghatei M, Van Noorden S, Playford RJ & Calam J 2002 'Nitric oxide regulates the release of somatostatin from cultured gastric rabbit primary D-cells' Gastroenterology 123, (2) 566-576
Berlanga J, Prats P, Remirez D, Gonzalez R, Lopez-Saura P, Aguiar J, Ojeda M, Boyle JJ, Fitzgerald AJ 2002 'Prophylactic use of epidermal growth factor reduces ischemia/reperfusion intestinal damage' Am J Pathol 161, (2) 373-379 Author Site , DOI
Playford RJ 2002 'Homeobox genes: going for growth' Gut 50, (4) 447-448 Author Site , DOI
Khan Z, Nair P, O'Shea C, Spiers N, Playford RJ & Wicks AC 2002 'Does Helicobacter pylori eradication reduce the long-term requirements for acid suppressants in patients with a history of peptic ulcer disease in general practice? Results from a four-year longitudinal study' Scand J Gastroenterol 37, (2) 144-147 Author Site , DOI
Ashrafian H, Taylor-Robinson SD, Calam J & Playford RJ 2002 'Once you start, you can't stop' Lancet 359, (9302) Author Site , DOI
Gee I, Playford RJ, Turner D, Sheldon N & Wicks AC 2002 'Cost analysis of breath test versus endoscopy for dyspepsia' Digestion 65, (4) 207-212
MURRAY-LYON IM 2001 'Liver biopsy: "blind" or under ultrasound control Reply' Gut 49, (1) 157-158 , DOI
Marchbank T, Cox HM, Goodlad RA, Giraud AS, Moss SF, Poulsom R, Wright NA, Jankowski J & Playford RJ 2001 'Effect of ectopic expression of rat trefoil factor family 3 (intestinal trefoil factor) in the jejunum of transgenic mice' J Biol Chem 276, (26) 24088-24096 Author Site , DOI
Playford RJ, MacDonald CE, Calnan DP, Floyd DN, Podas T, Johnson W, Wicks AC, Bashir O & Marchbank T 2001 'Co-administration of the health food supplement, bovine colostrum, reduces the acute non-steroidal anti-inflammatory drug-induced increase in intestinal permeability' Clin Sci (Lond) 100, (6) 627-633 Author Site
Berlanga-Acosta J, Playford RJ, Mandir N & Goodlad RA 2001 'Gastrointestinal cell proliferation and crypt fission are separate but complementary means of increasing tissue mass following infusion of epidermal growth factor in rats' Gut 48, (6) 803-807
Playford RJ, Wicks ACB & Macdonald CE 2001 'Surveillance for Barrett's oesophagus - Appropriate practice must be studied - Response' BRITISH MEDICAL JOURNAL 322, (7294) 1126-1126 Author Site
Playford RJ 2001 'Landscaper seeks remunerative position' Gut 48, (5) 594-595 Author Site , DOI
Sinha A, Nightingale JM, West KP, Berlanga-Acosta J & Playford RJ 2001 'Epidermal growth factor enemas are effective in the treatment of left-sided ulcerative colitis' GASTROENTEROLOGY 120, (5) A11-A12 Author Site , DOI
Sinha A, Nightingale JMD, West KP, Berlanga-Acosta J & Playford RJ 2001 'Can left-sided ulcerative colitis be treated with Epidermal Growth Factor enemas?' GUT 48, A1-A1 Author Site
Caballero ME, Berlanga J, Ramirez D, Lopez-Saura P, Gozalez R, Floyd DN, Marchbank T & Playford RJ 2001 'Epidermal growth factor reduces multiorgan failure induced by thioacetamide' Gut 48, (1) 34-40
Macdonald CE, Wicks AC & Playford RJ 2000 'Final results from 10 year cohort of patients undergoing surveillance for Barrett's oesophagus: observational study' BMJ 321, (7271) 1252-1255
Calnan DP, Fagbemi A, Berlanga-Acosta J, Marchbank T, Sizer T, Lakhoo K, Edwards AD & Playford RJ 2000 'Potency and stability of C terminal truncated human epidermal growth factor' Gut 47, (5) 622-627 Author Site , DOI
Playford RJ, Wright NA & Marchbank T 2000 'Endogenous peptides and peptide therapy in gut defense and repair' Drug News Perspect 13, (6) 330-336 Author Site
Playford RJ, Macdonald CE & Johnson WS 2000 'Colostrum and milk-derived peptide growth factors for the treatment of gastrointestinal disorders' Am J Clin Nutr 72, (1) 5-14 Author Site , DOI
Berlanga J, Playford RJ, Mandir N & Goodlad RA 2000 'The temporal changes in colonic cell proliferation and crypt branching following EGF infusion' GUT 46, A55-A55 Author Site
Goodlad RA, Mandir N, Meeran K, Ghatei MA, Bloom SR & Playford RJ 2000 'Does the response of the intestinal epithelium to keratinocyte growth factor vary according to the method of administration?' Regul Pept 87, (1-3) 83-90
Wong WM, Playford RJ & Wright NA 2000 'Peptide gene expression in gastrointestinal mucosal ulceration: ordered sequence or redundancy?' Gut 46, (2) 286-292 Author Site , DOI
Shah S, Mayberry JF, Wicks AC, Rees Y & Playford RJ 1999 'Liver biopsy under ultrasound control: implications for training in the Calman era' Gut 45, (4) 628-629 Author Site , DOI
Berlanga J, Caballero E, Prats P, López Saura P & Playford RJ 1999 '[The role of the epidermal growth factor in cell and tissue protection]' Med Clin (Barc) 113, (6) 222-229 Author Site
Playford RJ, Podas T & Modlin I 1999 'Pantoprazole, Prout and the proton pump' Hosp Med 60, (7) 500-504 Author Site
Calnan DP, Westley BR, May FE, Floyd DN, Marchbank T & Playford RJ 1999 'The trefoil peptide TFF1 inhibits the growth of the human gastric adenocarcinoma cell line AGS' J Pathol 188, (3) 312-317 Author Site , DOI
Beck F, Chawengsaksophak K, Waring P, Playford RJ & Furness JB 1999 'Reprogramming of intestinal differentiation and intercalary regeneration in Cdx2 mutant mice' Proc Natl Acad Sci U S A 96, (13) 7318-7323 Author Site , DOI
Schmidt PH, Lee JR, Joshi V, Playford RJ, Poulsom R, Wright NA & Goldenring JR 1999 'Identification of a metaplastic cell lineage associated with human gastric adenocarcinoma' Lab Invest 79, (6) 639-646 Author Site
Playford RJ, Floyd DN, Macdonald CE, Calnan DP, Adenekan RO, Johnson W, Goodlad RA & Marchbank T 1999 'Bovine colostrum is a health food supplement which prevents NSAID induced gut damage' Gut 44, (5) 653-658
Lalani EN, Williams R, Jayaram Y, Gilbert C, Chaudhary KS, Siu LS, Koumarianou A, Playford R & Stamp GW 1999 'Trefoil factor-2, human spasmolytic polypeptide, promotes branching morphogenesis in MCF-7 cells' Lab Invest 79, (5) 537-546 Author Site
Jankowski J, McCucheon J, Marchbank T & Playford RJ 1999 'Pancreatic secretory trypsin inhibitor expression in Barrett's metaplasia correlates closely with non-neoplastic well differentiated epithelial phenotypes' GUT 44, A107-A107 Author Site
Marchbank T, Cox H, Goodlad R, Giraud AS, Moss S, Wright NA & Playford RJ 1999 'Transgenic mice overexpressing TFF3 (rat intestinal trefoil factor) within the jejunum have an increased regional resistance to intestinal damage but no difference in cell migration or apoptosis' GUT 44, A88-A88 Author Site
Efstathiou JA, Liu D, Wheeler JM, Kim HC, Beck NE, Ilyas M, Karayiannakis AJ, Mortensen NJ, Kmiot W 1999 'Mutated epithelial cadherin is associated with increased tumorigenicity and loss of adhesion and of responsiveness to the motogenic trefoil factor 2 in colon carcinoma cells' Proc Natl Acad Sci U S A 96, (5) 2316-2321 Author Site , DOI
Hanby AM, Poulsom R, Playford RJ & Wright NA 1999 'The mucous neck cell in the human gastric corpus: a distinctive, functional cell lineage' J Pathol 187, (3) 331-337 Author Site , DOI
Calnan DP, Westley BR, May FEB, Floyd DN, Marchbank T & Playford RJ 1999 'The trefoil peptide TFF1 inhibits the growth of the human gastric adenocarcinoma cell line ags' Journal of Pathology 188, (3) 312-317 , DOI
Playford RJ & Wright NA 1998 'Peptides and peptic ulceration' QJM 91, (10) 661-665 Author Site , DOI
Karayiannakis AJ, Syrigos KN, Efstathiou J, Valizadeh A, Noda M, Playford RJ, Kmiot W & Pignatelli M 1998 'Expression of catenins and E-cadherin during epithelial restitution in inflammatory bowel disease' J Pathol 185, (4) 413-418 Author Site , DOI
Seare NJ & Playford RJ 1998 'Growth factors and gut function' Proc Nutr Soc 57, (3) 403-408 Author Site , DOI
Marchbank T, Westley BR, May FE, Calnan DP & Playford RJ 1998 'Dimerization of human pS2 (TFF1) plays a key role in its protective/healing effects' J Pathol 185, (2) 153-158 Author Site , DOI
Marchbank T, Westley BR, May FEB, Calnan DP & Playford RJ 1998 'Dimerization of human pS2 (TFF1) plays a key role in its protective/healing effects' The Journal of Pathology 185, (2) 153-158 , DOI
Playford RJ 1998 'Tales from the human crypt--intestinal stem cell repertoire and the origins of human cancer' J Pathol 185, (2) 119-122 Author Site , DOI
Playford RJ, Marchbank T, Mandir N, Higham A, Meeran K, Ghatei MA, Bloom SR & Goodlad RA 1998 'Effects of keratinocyte growth factor (KGF) on gut growth and repair' J Pathol 184, (3) 316-322 Author Site , DOI
Playford RJ, Marchbank T, Mandir N, Higham A, Meeran K, Ghatei MA, Bloom SR & Goodlad RA 1998 'Effects of keratinocyte growth factor (KGF) on gut growth and repair' J Pathol 184, (3) 316-322 , DOI
Playford RJ, Marchbank T, Mandir N, Higham A, Meeran K, Ghatei MA, Bloom SR & Goodlad RA 1998 'Effects of keratinocyte growth factor (KGF) on gut growth and repair' Journal of Pathology 184, (3) 316-322 , DOI
Berlanga J, Caballero ME, Ramirez D, Torres A, Valenzuela C, Lodos J & Playford RJ 1998 'Epidermal growth factor protects against carbon tetrachloride-induced hepatic injury' Clin Sci (Lond) 94, (3) 219-223 Author Site , DOI
Marchbank T, Freeman TC & Playford RJ 1998 'Human pancreatic secretory trypsin inhibitor. Distribution, actions and possible role in mucosal integrity and repair' Digestion 59, (3) 167-174 Author Site , DOI
Jordinson M, Playford RJ & Calam J 1997 'Effects of a panel of dietary lectins on cholecystokinin release in rats' Am J Physiol 273, (4) G946-G950 Author Site , DOI
Macdonald CE, Wicks AC & Playford RJ 1997 'Ten years' experience of screening patients with Barrett's oesophagus in a university teaching hospital' Gut 41, (3) 303-307
Playford RJ & Macdonald CE 1997 'Growth factors in saliva' Lancet 350, (9074) Author Site , DOI
McKenzie C, Marchbank T, Playford RJ, Otto W, Thim L & Parsons ME 1997 'Pancreatic spasmolytic polypeptide protects the gastric mucosa but does not inhibit acid secretion or motility' Am J Physiol 273, (1 Pt 1) G112-G117 Author Site , DOI
McKenzie C, Marchbank T, Playford RJ, Otto W, Thim L & Parsons ME 1997 'Pancreatic spasmolytic polypeptide protects the gastric mucosa but does not inhibit acid secretion or motility' American Journal of Physiology - Gastrointestinal and Liver Physiology 273, (1 36-1)
McKenzie C, Marchbank T, Playford RJ, Otto W, Thim L & Parsons ME 1997 'Pancreatic spasmolytic polypeptide protects the gastric mucosa but does not inhibit acid secretion or motility' AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 273, (1) G112-G117 Author Site
Playford RJ 1997 'Recombinant peptides for gastrointestinal ulceration: still early days' Gut 40, (2) 286-287 Author Site , DOI
Playford RJ & Macdonald CE 1997 'Peptide YY and electrolyte homeostasis' Gut 40, (1) Author Site , DOI
Playford RJ 1997 'Trefoil peptides: what are they and what do they do?' J R Coll Physicians Lond 31, (1) 37-41 Author Site
Playford R 1996 'Cytokines and Helicobacter pylori--a growth area' Gut 39, (6) 881-882 Author Site , DOI
Playford RJ & Cox HM 1996 'Peptide YY and neuropeptide Y: two peptides intimately involved in electrolyte homeostasis' Trends Pharmacol Sci 17, (12) 436-438 Author Site , DOI
Playford RJ & Macdonald CE 1996 'Safety of bismuth' Aliment Pharmacol Ther 10, (6) 1035-1036 Author Site , DOI
Macdonald CE & Playford RJ 1996 'Iron deficiency anaemia and febrile convulsions. ...and coeliac disease' BMJ 313, (7066) Author Site , DOI
Goodlad RA, Boulton R & Playford RJ 1996 'Comparison of the mitogenic activity of human epidermal growth factor I-53 and epidermal growth factor I-48 in vitro and in vivo' Clin Sci (Lond) 91, (4) 503-507 Author Site , DOI
Playford RJ, Hanby AM, Gschmeissner S, Peiffer LP, Wright NA & McGarrity T 1996 'The epidermal growth factor receptor (EGF-R) is present on the basolateral, but not the apical, surface of enterocytes in the human gastrointestinal tract' Gut 39, (2) 262-266
Jordinson M, Deprez PH, Playford RJ, Heal S, Freeman TC, Alison M & Calam J 1996 'Soybean lectin stimulates pancreatic exocrine secretion via CCK-A receptors in rats' Am J Physiol 270, (4 Pt 1) G653-G659 Author Site , DOI
Playford RJ, Marchbank T, Goodlad RA, Chinery RA, Poulsom R & Hanby AM 1996 'Transgenic mice that overexpress the human trefoil peptide pS2 have an increased resistance to intestinal damage' Proc Natl Acad Sci U S A 93, (5) 2137-2142 Author Site , DOI
Marchbank T, Chinery R, Hanby AM, Poulsom R, Elia G & Playford RJ 1996 'Distribution and expression of pancreatic secretory trypsin inhibitor and its possible role in epithelial restitution' Am J Pathol 148, (3) 715-722 Author Site
Hanby AM, Chinery R, Poulsom R, Playford RJ & Pignatelli M 1996 'Downregulation of E-cadherin in the reparative epithelium of the human gastrointestinal tract' Am J Pathol 148, (3) 723-729 Author Site
Playford RJ & Shaw-Smith C 1996 'Growth factors and ulcerative gastrointestinal disease' Baillieres Clin Gastroenterol 10, (1) 135-149 Author Site
Playford RJ & Wright NA 1996 'Why is epidermal growth factor present in the gut lumen?' Gut 38, (3) 303-305 Author Site , DOI
Playford RJ, Boulton R, Ghatei MA, Bloom SR, Wright NA & Goodlad RA 1996 'Comparison of the effects of transforming growth factor alpha and epidermal growth factor on gastrointestinal proliferation and hormone release' Digestion 57, (5) 362-367 Author Site , DOI
Playford RJ 1995 'Peptides and gastrointestinal mucosal integrity' Gut 37, (5) 595-597 Author Site , DOI
Marchbank T, Goodlad RA, Lee CY & Playford RJ 1995 'Luminal epidermal growth factor is trophic to the small intestine of parenterally fed rats' Clin Sci (Lond) 89, (2) 117-120 Author Site , DOI
Playford RJ, Wright NA & Goodlad RA 1995 'Luminal nutrition and gut growth' Gut 36, (6) Author Site , DOI
Chinery R & Playford RJ 1995 'Combined intestinal trefoil factor and epidermal growth factor is prophylactic against indomethacin-induced gastric damage in the rat' Clin Sci (Lond) 88, (4) 401-403 Author Site , DOI
Playford RJ, Mehta S, Upton P, Rentch R, Moss S, Calam J, Bloom S, Payne N, Ghatei M 1995 'Effect of peptide YY on human renal function' Am J Physiol 268, (4 Pt 2) F754-F759 Author Site , DOI
Goodlad RA & Playford RJ 1995 'Epidermal growth factor and intestinal growth' Gastroenterology 108, (4) 1330-1331 Author Site , DOI
Playford RJ & Goodlad RA 1995 'Is glutamine required for the trophic effect of epidermal growth factor?' Surgery 117, (3) Author Site , DOI
Playford RJ, Hanby AM, Patel K & Calam J 1995 'Influence of inflammatory bowel disease on the distribution and concentration of pancreatic secretory trypsin inhibitor within the colon' Am J Pathol 146, (2) 310-316 Author Site
Playford RJ, Marchbank T, Calnan DP, Calam J, Royston P, Batten JJ & Hansen HF 1995 'Epidermal growth factor is digested to smaller, less active forms in acidic gastric juice' Gastroenterology 108, (1) 92-101
Playford RJ, Marchbank T, Chinery R, Evison R, Pignatelli M, Boulton RA, Thim L & Hanby AM 1995 'Human spasmolytic polypeptide is a cytoprotective agent that stimulates cell migration' Gastroenterology 108, (1) 108-116
Playford RJ, Hanby AM, Quinn C & Calam J 1994 'Influence of inflammation and atrophy on pancreatic secretory trypsin inhibitor levels within the gastric mucosa' Gastroenterology 106, (3) 735-741
Patel K, Hanby AM, Ahnen DJ, Playford RJ & Wright NA 1994 'The kinetic organization of the ulcer-associated cell lineage (UACL): delineation of a novel putative stem-cell region' Epithelial Cell Biol 3, (4) 156-160 Author Site
Playford RJ, King AW, Deprez PH, De-Belleroche J, Freeman TC & Calam J 1993 'Effects of diet and the cholecystokinin antagonist; devazepide (L364,718) on CCK mRNA, and tissue and plasma CCK concentrations' Eur J Clin Invest 23, (10) 641-647 Author Site , DOI
Playford RJ, Woodman AC, Clark P, Watanapa P, Vesey D, Deprez PH, Williamson RC & Calam J 1993 'Effect of luminal growth factor preservation on intestinal growth' Lancet 341, (8849) 843-848 Author Site , DOI
Playford RJ, Benito-Orfila MA, Nihoyannopoulos P, Nandha KA, Cockcroft J, Todd S, Ghatei MA, Domin J, Bloom SR 1992 'Effects of peptide YY on the human cardiovascular system: reversal of responses to vasoactive intestinal peptide' Am J Physiol 263, (4 Pt 1) E740-E747 Author Site , DOI
Playford RJ 1992 'Allegation of sexual assault following midazolam sedation in a man' Anaesthesia 47, (9) Author Site , DOI
Beardshall K, Deprez P, Playford RJ, Alexander M & Calam J 1992 'Effect of chymotrypsin on human cholecystokinin release: use of clostripain in the validation of a new radioimmunoassay' Regul Pept 40, (1) 1-12 Author Site , DOI
Beardshall K, Moss S, Gill J, Levi S, Ghosh P, Playford RJ & Calam J 1992 'Suppression of Helicobacter pylori reduces gastrin releasing peptide stimulated gastrin release in duodenal ulcer patients' Gut 33, (5) 601-603 Author Site , DOI
Moss SF, Playford RJ, Ayesu K, Li SK & Calam J 1992 'pH-dependent secretion of gastrin in duodenal ulcer disease: effect of suppressing Helicobacter pylori' Digestion 52, (3-4) 173-178 Author Site , DOI
Playford RJ, Schulenburg E, Herrington CS & Hodgson HJ 1992 'Whipple's disease complicated by a retinal Jarisch-Herxheimer reaction: a case report' Gut 33, (1) 132-134 Author Site , DOI
Playford RJ, Batten JJ, Freeman TC, Beardshall K, Vesey DA, Fenn GC, Baron JH & Calam J 1991 'Gastric output of pancreatic secretory trypsin inhibitor is increased by misoprostol' Gut 32, (11) 1396-1400 Author Site , DOI
Deprez PH, Ghosh P, Goodlad RA, Lacey SL, Millership S, Playford RJ, Lee CY & Calam J 1991 'Hypergastrinaemia: a new mechanism' Lancet 338, (8764) 410-411 Author Site , DOI
Playford RJ, Vesey DA, Haldane S, Alison MR & Calam J 1991 'Dose-dependent effects of fentanyl on indomethacin-induced gastric damage' Digestion 49, (4) 198-203 Author Site , DOI
Freeman TC, Playford RJ, Quinn C, Beardshall K, Poulter L, Young J & Calam J 1990 'Pancreatic secretory trypsin inhibitor in gastrointestinal mucosa and gastric juice' Gut 31, (11) 1318-1323 Author Site , DOI
Playford RJ, Domin J, Beacham J, Parmar KB, Tatemoto K, Bloom SR & Calam J 1990 'Preliminary report: role of peptide YY in defence against diarrhoea' Lancet 335, (8705) 1555-1557 Author Site , DOI
Playford RJ, Matthews CH, Campbell MJ, Delves HT, Hla KK, Hodgson HJ & Calam J 1990 'Bismuth induced encephalopathy caused by tri potassium dicitrato bismuthate in a patient with chronic renal failure' Gut 31, (3) 359-360 Author Site , DOI
Levi S, Beardshall K, Swift I, Foulkes W, Playford R, Ghosh P & Calam J 1989 'Antral Helicobacter pylori, hypergastrinaemia, and duodenal ulcers: effect of eradicating the organism' BMJ 299, (6714) 1504-1505 Author Site , DOI
Levi S, Beardshall K, Haddad G, Playford R, Ghosh P & Calam J 1989 'Campylobacter pylori and duodenal ulcers: the gastrin link' Lancet 1, (8648) 1167-1168 Author Site , DOI
Grunewald RA, Smith PL, Nihoyannopoulos P, Playford RJ, Levi S & Hodgson HJ 1989 'Right ventricular pacing wire thrombus presenting as pyrexia of unknown origin' Clin Cardiol 12, (2) 106-108 Author Site , DOI
Playford RJ, Dawnay A, Cattell WR & Landon J 1985 'The development of a fluoroimmunoassay for beta-2-microglobulin in serum' Ann Clin Biochem 22 ( Pt 2), 166-170 Author Site , DOI
Letters
Playford R, Wright N & Goodlad R 1996 'Concentrations of epidermal growth factor in human saliva and gastric juice' Gut 38, (4) 629-630 Author Site , DOI
Chapters
Marchbank T & Playford RJ 2014 'Colostrum: Its Health Benefits, in Milk and Dairy Products as Functional Foods' in Kanekanian A Milk and Dairy Products as Functional Foods John Wiley & Sons PEARL
Playford RJ & Podolsky DK 2010 'Biological Basis of Healing and Repair in Remission and Relapse' Inflammatory Bowel Disease: Translating basic science into clinical practice 170-181 , DOI
Conference Papers
Playford R, Davison G, Marchbank T, March D & Thatcher R 2016 'OC-023 Randomised Trial: The Nutriceutical Zinc Carnosine Works with Bovine Colostrum in Truncating Heavy Exercise Induced Increase in Gut Permeability through Actions on Tight Junctions, Apoptosis and Heat Shock Protein 70 Production' BMJ A14.3-A15 , DOI
Marchbank T, Davison G, Oakes JR, Ghatei M, Patterson M, Rolfs J & Playford RJ 2010 'OC-083 Clinical trial: influence of bovine colostrum on intestinal permeability in healthy athletes after heavy exercise' BMJ A34.2-A35 , DOI
Marchbank T, Elia G & Playford RJ 2009 'Intestinal Protective Effect of a Commercial FISH Protein Hydrolysate Preparation' A716-A716
Mahmood A, Marchbank T, Harten S, Maxwell PH, Ghosh S & Playford RJ 2007 'Administration of dimethyloxalylglycine (Dmog) as a novel gastrointestinal repair strategy' A405-A405
Mahmood A, Marchbank T, Harten SK, Maxwell PH, Ghosh S & Playford RJ 2007 'Administration of dimethyloxalylglycine as a novel gastrointestinal repair strategy' A31-A31
van Heel DA, Hunt KA, Ghosh S, King K, Gabe S, Mathew CG, Forbes A & Playford RJ 2006 'Detection of muramyl dipeptide sensing pathway defects in patients with Crohn's disease' A17-A17
van Heel DA, Hunt KA, Ghosh S, Herve M & Playford RJ 2006 'Normal responses to specific NOD1 activating peptidoglycan agonists in the presence of the NOD2 frameshift and other mutations in Crohn's disease' A76-A76
Chaudhary R, Butler M, Playford R & Ghosh S 2006 'Under appropriate conditions lymphocyte apoptosis is caused not only by infliximab and adalimumab but also by etanercept in vitro' A82-A82
Cibrian D, Ajamieh H, Berlanga J, Leon OS, Alba JS, Kim MJT, Marchbank T, Boyle JJ, Freyre F 2006 'Use of growth hormone releasing peptide-6 for the prevention of hepatic and multi organ failure' A28-A28
Cibrian D, Ajamieh H, Berlanga J, Leon O, Alba J, Kim M, Marchbank T, Boyle J, Ntatsaki E 2006 'Use of growth hormone releasing peptide-6 for the prevention of hepatic and multi organ failure' A337-A337
Hunt KA, McGovern DPB, Kumar PJ, Ghosh S, Travis SPL, Walters JRF, Jewell DP, Playford RJ & van Heel DA 2005 'A common CTLA4 haplotype associated with coeliac disease' A37-A37
van Heel DA, Ghosh S, Butler M, Hunt KA, Lundberg A, Ahmad T, McGovern DPB, Onnie C, Negoro K 2005 'Amplification of Toll-like receptor sensitivity by muramyl dipeptide is impaired in Crohn's disease associated NOD2 mutations' A1-A1
Chaudhary R, Butler M, Playford RJ & Ghosh S 2005 'Comparison of depsipher with annexin-V in quantifying apoptosis induced by infliximab, etanercept, and adalimumab in CD4+T cells and peripheral blood mononuclear cells' A2-A2
Chaudhary R, Butler M, Playford R & Ghosh S 2005 'Inhibition of proliferation of stimulated peripheral blood mononuclear cells by different anti-TNF therapies' A99-A99
Mahmood A, Melley L, Fitzgerald AJ, Ghosh S & Playford RJ 2005 'Phase I/II trial of trefoil factor family 3 (TFF3) enema therapy with oral mesalazine for mild to moderate left-sided colitis' A93-A93
FitzGerald AJ, Rai PS, Marchbank T, Taylor GW, Ghosh S, Ritz B & Playford RJ 2005 'Reparative properties of a commercial fish protein hydrolysate preparation' A5-A5
FitzGerald AJ, Rai PS, Marchbank T, Taylor GW, Ghosh S, Ritz BW & Playford RJ 2005 'Reparative properties of a commercial fish protein hydrolysate preparation' A219-A220
Ghosh S, Jackson J, Tait P, Stocks J, Walters J, Sharif A & Playford R 2004 'A prospective comparison of mesenteric angiography with wireless capsule endoscopy in the diagnosis of obscure gastrointestinal haemorrhage' A5-A6
Butler M, Winstanley S, Van Heel D, Lombardi G, Lechler R, Playford R & Ghosh S 2004 'Expression of NOD2 by intestinal epithelial cells in an in vitro M cell model' A64-A64
Butler M, Winstanley S, Lombardi G, Lechler R, Playford R & Ghosh S 2004 'Expression of toll-like receptors by intestinal epithelial cells in an in vitro M cell model' A64-A65
FitzGerald AJ, Pu M, Marckbank T, Westley BR, May FEB, Boyle J, Yadollahi-Farsani M, Ghosh S & Playford RJ 2004 'Synergistic effects of systemic trefoil factor family 1 and epidermal growth factor in a rat model of colitis' A96-A96
FitzGerald AJ, Pu M, Marchbank T, Westley BR, May FEB, Boyle J, Yadollahi-Farsani M, Ghosh S & Playford RJ 2004 'Synergistic effects of systemic trefoil factor family 1 and epidermal growth factor in a rat model of colitis' A284-A284
Ghosh S, Stocks J, Sharif A, Walters J & Playford R 2004 'Wireless capsule endoscopy in upper endoscopy, push enteroscopy and colonoscopy negative obscure gastrointestinal haemorrhage' A73-A73
FitzGerald AJ, Marchbank T, Boyle J, Ghosh S & Playford RJ 2003 'The nutriceutical bovine colostrum for the treatment of dextran sulfate sodium induced colitis in rats' A64-A64
Playford RJ 2001 'Peptide therapy and the gastroenterologist: colostrum and milk-derived growth factors' 101-106 , DOI
Marchbank T, Cox H, Goodlad R, Giraud AS, Moss S, Wright NA & Playford RJ 1999 'Transgenic mice overexpressing TFF3 (rat intestinal trefoil factor) within the jejunum have an increased regional resistance to intestinal damage but no difference in cell migration or apoptosis' A920-A920
Marchbank T & Playford RJ 1998 'Bovine colostrum or TGFβ1 (A major bioactive constituent of colostrum) are prophylactic against indomethacin-induced, gastric injury' Elsevier BV A214-A215 , DOI
Marchbank T & Playford RJ 1998 'Bovine colostrum or TGF beta (a major bioactive constituent of colostrum) are prophylactic against indomethacin-induced gastric injury' A68-A68
Marchbank T, Westley BR, May FEB & Playford RJ 1997 'Cys(58) of human pS2 plays a key role in the stimulation of healing in vitro and in vivo' A45-A45
Playford RJ, Adenekan RO, Marchbank T, Boulton R, Johnson W & Goodlad RA 1997 'Bovine colostrum is prophylactic against indomethacin-induced intestinal injury' A394-A394
Playford RJ, Marchbank T, Mandir N, Higham A, Meeran K, Ghatei MA, Bloom SR & Goodlad RA 1997 'Keratinocyte growth factor (KGF) stimulates gut growth but is not a cytoprotective agent and does not stimulate migration of the human colonic carcinoma cell line HT29' A898-A898
Playford RJ, Adenekan RO, Marchbank T, Boulton R, Johnson W & Goodlad R 1997 'Bovine colostrum is prophylactic against indomethacin-induced intestinal injury' F285-F285
Playford RJ, Marchbank T, Mandir N, Higham A, Meeran K, Ghatei MA, Bloom SR & Goodlad RA 1997 'Keratinocyte growth factor (KGF) stimulates gut growth but is not a cytoprotective agent and does not stimulate migration of the human colonic carcinoma cell line HT29' P315-P315
Playford RJ, Marchbank T, Goodlad RA, Chinery RA, Poulsom R, Hanby AM & Wright NA 1996 'Transgenic mice which overexpress the human trefoil peptide, pS2, have an increased resistance to intestinal damage' A231-A231
Marchbank T, Poulsom R, Hanby AM & Playford RJ 1995 'Distribution of human pancreatic secreteory trypsin inhibitor (PSTI) using in situ hybridisation and immunological staining techniques' Elsevier BV A737-A737 , DOI
PLAYFORD RJ, MARCHBANK T, CALNAN D, CALAM J & HANSEN H 1994 'HUMAN EGF IS CLEAVED TO SMALLER, LESS ACTIVE, FORMS IN ACIDIC HUMAN GASTRIC-JUICE' A628-A628