Establishing 3D meningioma culture model

MPhil/PhD studentship available full time or part-time

Project title:  Establishing 3D meningioma culture model

Reference number: 18-19-010R2                  

Start date: 1 October 2019

Director of studiesProfessor Oliver Hanemann

2nd supervisor: Dr David Hilton

3rd supervisor:  Dr Emanuela Ercolano 

The Faculty of Medicine and Dentistry are pleased to consider applications from highly motivated PhD candidates with an interest in cancer and knowledge of in vitro models, to join their exciting and rapidly expanding programme of internationally-rated research. The Institute of Translational and Stratified (ITSMED) is at the core of FoMD. ITSMED is translational oriented and works across traditional boundaries. The Institute brings together the world-class research strengths of the University. The candidate would work as part of a team with a successful track record in brain tumour research, including brain tumour cell cultures (see Stepanova et al Cancer Res 2017, Bassiri et al EBiomedicine 2017, Dunn et al. EBiomedicine 2018).

The studentship is aiming to develop and study a 3D model of meningioma and test available drugs, building on our previous work. The supervisory team brings complementary expertise in translational research, cell biology and neuropathology. Training will be provided for the development to enable the trainee to conduct high-quality and independent scientific research.

Meningiomas are tumours of the meninges and make up 20–30 per cent of all primary brain tumours of the central nervous system. Standard treatment is surgical resection. Nevertheless, about one third of meningiomas cannot be operated on and current chemotherapies are not effective; therefore, there is a need to identify new drug treatment.

The Faculty is committed to research excellence with a recent £25 million investment in staff and facilities. Medical research at FoMD was ranked first for outputs in REF2014.

Applications are invited from suitably qualified graduates that meet the following criteria:

  • Master’s or BSc with significant laboratory experience in relevant area.
  • A first class or upper second class honours degree.
  • Some experience in cell culture ideally of primary cultures.
  • Knowledge of cancer biology or related area.

International students must also have an academic IELTS score of 6.5 or above (with no less than 6.0 in any element).

For further information regarding the project, please contact Professor Oliver Hanemann. However, applications must be made in accordance with the details shown below.

Funding notes:

The studentship is supported for three years and includes full Home/EU tuition fees, and a stipend of an estimated £15,009 per annum (based on 19/20 stipend amounts). Applicants normally required to cover overseas fees will have to cover the difference between the Home/EU and the overseas tuition fee rates (£12,285 for 19/20). If you are selected you will be required to provide financial assurances.

To apply:

Follow the link and select ‘Apply’. Please mark the application for the attention of Amber Strong. If you have any questions on the admissions process contact 

The closing date for applications is 12 midnight on Sunday 2 June 2019. Shortlisted candidates will be invited for interview. We regret that we may not be able to respond to all applications.