Mechanisms of mitochondrial dynamics dysfunction in Lewy Bodies dementia

Project title:  Mechanisms of mitochondrial dynamics dysfunction in Lewy Bodies dementia

Reference:  PUPSMD-16-17-001R2 

Mode of attendance:  Only full-time applications can be considered on this occasion.

Start date: 1 October 2018

Director of Studies: Dr Shouqing Luo

2nd Supervisor: Professor Robert Fern

The Plymouth University Peninsula Schools of Medicine and Dentistry are seeking to attract PhD candidates of outstanding ability to join their exciting and rapidly expanding programme of internationally-rated research. The Plymouth University Peninsula Schools of Medicine and Dentistry are committed to research excellence with a recent £25 million investment in staff and facilities. Medical research at PUPSMD was ranked first for outputs in REF2014.

Applications are invited from suitably qualified graduates, 2:1 or above. International students must also have an academic IELTS score of 7.0 or above (with no less than 6.5 in any element).

Project description: 

Dementia diseases are a great challenge to the modern society. It is important to understand the pathways and mechanisms to the development of the devastating diseases, as characterisation of the molecular mechanisms of the diseases may reveal new potential therapeutic targets, leading to neuroprotection for the treatment of the diseases. The PhD studentship is aimed to unravel novel mechanisms to the pathogenesis of dementia diseases featured with protein aggregates, and investigate new therapeutic approaches for the diseases. Experiments will be performed using molecular and cell biological tools with cell lines, patient-derived IPSC-induced neurons, and other physiologically relevant models. Training will be provided for the development of both knowledge and technical skills to enable the trainee to conduct high-quality and independent scientific research in the fields of autophagy and programmed cell death.

For further information regarding the project, please contact Dr Shouqing Luo. However, applications must be made in accordance with the details shown below.

Funding notes:

The studentship is supported for three years and includes full home/EU tuition fees plus a stipend of £14,777 per annum. The studentship will only fully fund those applicants who are eligible for home/EU fees with relevant qualifications. Applicants normally required to cover overseas fees will have to cover the difference between the home/EU and the overseas tuition fee rates. For the 18/19 academic year, the difference in fee is £10,610. If you are selected you will be required to provide financial assurances. 

Please note that due to funder requirements, only full-time applications can be considered on this occasion.

To apply:

Follow the link https://www.plymouth.ac.uk/student-life/your-studies/research-degrees/applicants-and-enquirers and select ‘Apply’ to access the application form. Please mark the application with reference PUPSMD-16-17-001 R2 and for the attention of Francesca Niedzielski. Please note: you do not need to submit a project proposal with your application. 

Further information on the application process. If you have any questions on the admissions process contact pupsmd-researchdegreesadmissions@plymouth.ac.uk.  

The closing date for applications is 12 noon on Friday 13 April 2018

Shortlisted candidates will be invited for interview. We regret that we may not be able to respond to all applications. Applicants who have not received an offer of a place by 31 May 2018 should consider their application has been unsuccessful on this occasion.