
Profiles
Dr Emanuela Ercolano
Research Technician
Peninsula Medical School (Faculty of Health: Medicine, Dentistry and Human Sciences)
Key publications are highlighted
Journals
Articles
2015
'The scaffold protein KSR1, a novel therapeutic target for the treatment of Merlin-deficient tumors'
Oncogene
35,
(26)
3443-3453
, DOI
PEARL
2012
'The role of insulin-like growth factors signaling in merlin-deficient human schwannomas'
Glia
60,
(11)
1721-1733
, DOI
PEARL
2012
'The role of insulin-like growth factors signaling in merlin-deficient human schwannomas. Ammoun S, Schmid MC, Ristic N, Zhou L, Hilton D, Ercolano E, Carroll C, Hanemann CO. Glia. 2012 Nov;60(11):1721-33. doi: 10.1002/glia.22391. Epub 2012 Jul 20'
Glia
2012
'Insulin-like growth factor-binding protein-1 (IGFBP-1) regulates human schwannoma proliferation, adhesion and survival'
Oncogene
31,
(13)
1710-1722
, DOI
2011
'Merlin-deficient human tumors show loss of contact inhibition and activation of Wnt/β-catenin signaling linked to the PDGFR/Src and Rac/PAK pathways'
Neoplasia
13,
(12)
1101-1112
, DOI
2008
'A concise entry into nonsymmetrical alkyl polyamines'
ORGANIC LETTERS
10,
(19)
4199-4202
, DOI
2008
'Synthesis and biological evaluation of isosteric analogues of FK866, an inhibitor of NAD salvage'
ChemMedChem
3,
(5)
771-779
, DOI
2006
'Modulation of calcium signalling by the actin-binding protein cofilin'
Biochem Biophys Res Commun
348,
(1)
109-114
, DOI
2005
'The cell cycle: a new entry in the field of Ca2+ signaling'
Cell Mol Life Sci
62,
(21)
2405-2413
, DOI
2003
'The M-phase-promoting Factor Modulates the Sensitivity of the Ca2+Stores to Inositol 1,4,5-Trisphosphate via the Actin Cytoskeleton'
Journal of Biological Chemistry
278,
(43)
42505-42514
, DOI
2003
'NAADP activates a Ca2+ current that is dependent on F-actin cytoskeleton'
FASEB J
17,
(13)
1907-1909
, DOI
2003
'Ca2+ signalling and membrane current activated by cADPr in starfish oocytes'
Pflugers Arch
446,
(5)
541-552
, DOI
2003
'A new transformation-regeneration procedure in the model legume Lotus japonicus: root explants as a source of large numbers of cells susceptible to Agrobacterium-mediated transformation'
Plant Cell Rep
21,
(8)
771-777
, DOI
2001
'The Rhizobium leguminosarum glnB gene is down-regulated during symbiosis'
Mol Gen Genet
264,
(5)
555-564
, DOI
Conference Papers
2015
'Abstract 704: Scaffold protein KSR1 is negatively regulated by merlin and promotes tumor development in merlin deficient tumors'
Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA
American Association for Cancer Research
, DOI
2012
'MERLIN DEFICIENT HUMAN TUMOURS SHOW LOSS OF CONTACT INHIBITION, ACTIVATION OF WNT/beta-CATENIN SIGNALING LINKED TO THE PDGFR/SRC AND RAC/PAK PATHWAYS'
5-6
2010
'IGF/IGFBP SIGNALING IN MERLIN-DEFICIENT TUMORS'
22-22
2003
'Activated M-phase-promoting factor (MPF) is exported from the nucleus of starfish oocytes to increase the sensitivity of the Ins(1,4,5)P3 receptors'
England
79-82
, DOI