Profiles
Mr Jamie Blackwell
Research Fellow
School of Biomedical Sciences (Faculty of Health)
Biography
Biography
Jamie is a PhD student in Biomedical Sciences. He works in the mitochondrial biology team, supervised by Dr Jane Carré, Dr Michael Wilde and Dr Charlie Affourtit. He is exploring the relationship between mitochondrial function and metabolomic profiles, in clinical conditions where loss of muscle mass and function are prevalent.
Previously, Jamie worked as a research technician in the University of Exeter, supporting nutritional research in human health and exercise performance. There he developed an interest in bioenergetics of skeletal muscle, picking up skills in biochemical analyses, including immunohistochemistry and mitochondrial respiration. His work has contributed to knowledge of fatigue, ergogenic aids for athlete performance, and muscle growth/maintenance. Related topics include the influence of the oral microbiome on factors related to metabolism.
He hopes that in studying metabolism at a cellular level, he will develop his understanding of muscle bioenergetics, and lead to translational work in the field of sarcopenia.
Qualifications
Jamie studied at the University of Wales, Bangor, where he completed a BSc in Sports Science, and an MSc in Exercise Physiology. There he conducted dissertation studies in the field of exercise immunology, looking at the effects of endurance exercise at environmental extremes and muscosal/systemic immune function.
Publications
Publications
Key publications
Key publications are highlighted
Journals
Articles
(2023) 'Vegan and Omnivorous High Protein Diets Support Comparable Daily Myofibrillar Protein Synthesis Rates and Skeletal Muscle Hypertrophy in Young Adults' The Journal of Nutrition 153, (6) 1680-1695 , DOI
(2022) 'Physiological and performance effects of dietary nitrate and N-acetylcysteine supplementation during prolonged heavy-intensity cycling' Journal of Sports Sciences 40, (23) 2585-2594 , DOI
(2022) 'The effect of various breath‐hold techniques on the cardiorespiratory response to facial immersion in humans' Experimental Physiology 108, (1) 50-62 , DOI
(2022) 'Mycoprotein ingestion within or without its wholefood matrix results in equivalent stimulation of myofibrillar protein synthesis rates in resting and exercised muscle of young men' British Journal of Nutrition 130, (1) 20-32 , DOI
(2022) 'Corrigendum for Pavis et al., volume 322, 2022, E231–E249' American Journal of Physiology-Endocrinology and Metabolism 323, (1) E122-E122 , DOI
(2022) 'Daily protein-polyphenol ingestion increases daily myofibrillar protein synthesis rates and promotes early muscle functional gains during resistance training' American Journal of Physiology-Endocrinology and Metabolism 322, (3) E231-E249 , DOI
(2021) 'Nitrate‐rich beetroot juice ingestion reduces skeletal muscle O<sub>2</sub> uptake and blood flow during exercise in sedentary men' The Journal of Physiology 599, (23) 5203-5214 , DOI
(2021) 'Neither Beetroot Juice Supplementation nor Increased Carbohydrate Oxidation Enhance Economy of Prolonged Exercise in Elite Race Walkers' Nutrients 13, (8) 2767-2767 , DOI
(2021) 'Network analysis of nitrate-sensitive oral microbiome reveals interactions with cognitive function and cardiovascular health across dietary interventions' Redox Biology 41, 101933-101933 , DOI
(2020) 'Mycoprotein ingestion stimulates protein synthesis rates to a greater extent than milk protein in rested and exercised skeletal muscle of healthy young men: a randomized controlled trial' The American Journal of Clinical Nutrition 112, (2) 318-333 , DOI
(2020) 'The effect of dietary nitrate supplementation on the speed-duration relationship in mice with sickle cell disease' Journal of Applied Physiology 129, (3) 474-482 , DOI
(2019) 'Dynamics of the power-duration relationship during prolonged endurance exercise and influence of carbohydrate ingestion' Journal of Applied Physiology 127, (3) 726-736 , DOI
(2018) 'Nitrate-responsive oral microbiome modulates nitric oxide homeostasis and blood pressure in humans' Free Radical Biology and Medicine 124, 21-30 , DOI
(2018) 'Lowering of blood pressure after nitrate-rich vegetable consumption is abolished with the co-ingestion of thiocyanate-rich vegetables in healthy normotensive males' Nitric Oxide 74, 39-46 , DOI
(2018) 'One-week cocoa flavanol intake increases prefrontal cortex oxygenation at rest and during moderate-intensity exercise in normoxia and hypoxia' Journal of Applied Physiology 125, (1) 8-18 , DOI
(2018) 'Discrete physiological effects of beetroot juice and potassium nitrate supplementation following 4-wk sprint interval training' Journal of Applied Physiology 124, (6) 1519-1528 , DOI
(2018) 'Beetroot juice ingestion during prolonged moderate-intensity exercise attenuates progressive rise in O<sub>2</sub> uptake' Journal of Applied Physiology 124, (5) 1254-1263 , DOI
(2016) 'Influence of iodide ingestion on nitrate metabolism and blood pressure following short-term dietary nitrate supplementation in healthy normotensive adults' Nitric Oxide 63, 13-20 , DOI
(2016) 'Muscle metabolic and neuromuscular determinants of fatigue during cycling in different exercise intensity domains' Journal of Applied Physiology 122, (3) 446-459 , DOI
(2016) 'Influence of dietary nitrate supplementation on physiological and muscle metabolic adaptations to sprint interval training' Journal of Applied Physiology 122, (3) 642-652 , DOI
(2016) 'Improvement in blood pressure after short-term inorganic nitrate supplementation is attenuated in cigarette smokers compared to non-smoking controls' Nitric Oxide 61, 29-37 , DOI
(2016) 'Intermittent walking, but not standing, improves postprandial insulin and glucose relative to sustained sitting: A randomised cross-over study in inactive middle-aged men' Journal of Science and Medicine in Sport 20, (3) 278-283 , DOI
(2016) 'Two weeks of watermelon juice supplementation improves nitric oxide bioavailability but not endurance exercise performance in humans' Nitric Oxide 59, 10-20 , DOI
(2016) 'The mechanistic bases of the power–time relationship: muscle metabolic responses and relationships to muscle fibre type' The Journal of Physiology 594, (15) 4407-4423 , DOI
(2015) 'Influence of beetroot juice supplementation on intermittent exercise performance' European Journal of Applied Physiology 116, (2) 415-425 , DOI
(2015) 'A single dose of sodium nitrate does not improve oral glucose tolerance in patients with type 2 diabetes mellitus' Nutrition Research 35, (8) 674-680 , DOI
(2015) 'Dietary nitrate modulates cerebral blood flow parameters and cognitive performance in humans: A double-blind, placebo-controlled, crossover investigation' Physiology & Behavior 149, 149-158 , DOI
(2015) '<scp>l</scp>-Citrulline supplementation improves O<sub>2</sub> uptake kinetics and high-intensity exercise performance in humans' Journal of Applied Physiology 119, (4) 385-395 , DOI
(2015) 'High-nitrate vegetable diet increases plasma nitrate and nitrite concentrations and reduces blood pressure in healthy women' Public Health Nutrition 18, (14) 2669-2678 , DOI
(2014) 'Changes in CEBPB expression in circulating leukocytes following eccentric elbow-flexion exercise' The Journal of Physiological Sciences 65, (1) 145-150 , DOI
(2014) 'Dietary nitrate accelerates postexercise muscle metabolic recovery and O<sub>2</sub>delivery in hypoxia' Journal of Applied Physiology 117, (12) 1460-1470 , DOI
(2014) 'Street football is a feasible health‐enhancing activity for homeless men: Biochemical bone marker profile and balance improved' Scandinavian Journal of Medicine & Science in Sports 24, (S1) 122-129 , DOI
(2013) 'Influence of dietary nitrate supplementation on physiological and cognitive responses to incremental cycle exercise' Respiratory Physiology & Neurobiology 193, 11-20 , DOI
(2013) 'Single and combined effects of beetroot juice and caffeine supplementation on cycling time trial performance' Applied Physiology, Nutrition, and Metabolism 39, (9) 1050-1057 , DOI
(2013) 'The Effect of Variable Doses of Inorganic Nitrate-Rich Beetroot Juice on Simulated 2000-m Rowing Performance in Trained Athletes' International Journal of Sports Physiology and Performance 9, (4) 615-620 , DOI
(2013) 'Musculoskeletal health profile for elite female footballers versus untrained young women before and after 16 weeks of football training' Journal of Sports Sciences 31, (13) 1468-1474 , DOI
(2013) 'Beetroot juice and exercise: pharmacodynamic and dose-response relationships' Journal of Applied Physiology 115, (3) 325-336 , DOI
(2013) 'No effect of acute l-arginine supplementation on O2 cost or exercise tolerance' European Journal of Applied Physiology 113, (7) 1805-1819 , DOI
(2013) 'Influence of dietary nitrate supplementation on human skeletal muscle metabolism and force production during maximum voluntary contractions' Pflügers Archiv - European Journal of Physiology 465, (4) 517-528 , DOI
(2013) 'Beetroot juice supplementation speeds O<sub>2</sub>uptake kinetics and improves exercise tolerance during severe-intensity exercise initiated from an elevated metabolic rate' American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 305, (12) R1441-R1450 , DOI
(2012) 'Effects of short-term dietary nitrate supplementation on blood pressure, O<sub>2</sub>uptake kinetics, and muscle and cognitive function in older adults' American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 304, (2) R73-R83 , DOI
(2012) 'Lifelong physical activity prevents an age‐related reduction in arterial and skeletal muscle nitric oxide bioavailability in humans' The Journal of Physiology 590, (21) 5361-5370 , DOI
(2012) 'Hydration Status, Fluid Intake, and Electrolyte Losses in Youth Soccer Players' International Journal of Sports Physiology and Performance 7, (4) 367-374 , DOI
(2012) 'Influence of acute dietary nitrate supplementation on 50 mile time trial performance in well-trained cyclists' European Journal of Applied Physiology 112, (12) 4127-4134 , DOI
(2011) 'Dietary nitrate reduces muscle metabolic perturbation and improves exercise tolerance in hypoxia' The Journal of Physiology 589, (22) 5517-5528 , DOI
(2011) 'Acute Dietary Nitrate Supplementation Improves Cycling Time Trial Performance' Medicine & Science in Sports & Exercise 43, (6) 1125-1131 , DOI
(2011) 'DIETARY NITRATE SUPPLEMENTATION ENHANCES MUSCLE EFFICIENCY DURING KNEE-EXTENSOR EXERCISE IN HUMANS' Japanese Journal of Physical Fitness and Sports Medicine 60, (1) 86-86 , DOI
(2010) 'Dietary nitrate supplementation reduces the O<sub>2</sub>cost of walking and running: a placebo-controlled study' Journal of Applied Physiology 110, (3) 591-600 , DOI
(2010) 'Influence of N-acetylcysteine administration on pulmonary O2 uptake kinetics and exercise tolerance in humans' Respiratory Physiology & Neurobiology 175, (1) 121-129 , DOI
(2010) 'Acute <scp>l</scp>-arginine supplementation reduces the O<sub>2</sub> cost of moderate-intensity exercise and enhances high-intensity exercise tolerance' Journal of Applied Physiology 109, (5) 1394-1403 , DOI
(2010) 'Acute and chronic effects of dietary nitrate supplementation on blood pressure and the physiological responses to moderate-intensity and incremental exercise' American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 299, (4) R1121-R1131 , DOI
(2010) 'Dietary nitrate supplementation enhances muscle contractile efficiency during knee-extensor exercise in humans' Journal of Applied Physiology 109, (1) 135-148 , DOI
(2009) 'Dietary nitrate supplementation reduces the O<sub>2</sub>cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans' Journal of Applied Physiology 107, (4) 1144-1155 , DOI
(2009) 'Influence of dichloroacetate on pulmonary gas exchange and ventilation during incremental exercise in healthy humans' Respiratory Physiology & Neurobiology 168, (3) 224-229 , DOI
(2005) 'Neutrophil degranulation response to 2 hours of excercise in a 30°C environment' AVIATION SPACE AND ENVIRONMENTAL MEDICINE 76, (11) 1068-1073
(2004) 'Salivary IgA response to prolonged exercise in a hot environment in trained cyclists' European Journal of Applied Physiology 93, (5-6) 665-671 , DOI
(2002) 'Salivary IgA response to prolonged exercise in a cold environment in trained cyclists' Medicine & Science in Sports & Exercise 34, (10) 1632-1637 , DOI